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The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
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- Dahlman, I (author)
- Karolinska Institutet
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- Sinha, I (author)
- Karolinska Institutet
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- Gao, H (author)
- Karolinska Institutet
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- Henriksson, J (author)
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- (creator_code:org_t)
- 2015-03-18
- 2015
- English.
- In: International Journal of Obesity. - : Springer Science and Business Media LLC. - 1476-5497 .- 0307-0565. ; 39:6, s. 910-919
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many small fat cells) in post-obesity.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
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- ref (subject category)
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- Dahlman, I
- Sinha, I
- Gao, H
- Brodin, D
- Thorell, A
- Rydén, M
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- Andersson, D P
- Henriksson, J
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- Ling, Charlotte
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- Arner, P
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- Lund University
- Karolinska Institutet
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